[Nov 17, 2021] BPS-Pharmacotherapy Practice Exam Dumps - 99% Marks In BPS Exam
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NEW QUESTION 65
Using a new assay, the following readings for Drug X concentration in a blood sample are obtained: 45 ng/mL, 43 ng/mL, 45 ng/mL, 44 ng/mL, 45 ng/mL, and 45 ng/mL. The true concentration of the drug was reported as 65 ng/mL using the gold-standard assay.
On the basis of these data, the new assay should be characterized in which of the following categories?
- A. Precise but not accurate
- B. Accurate but not precise
- C. Neither accurate nor precise
- D. Both accurate and precise
Answer: A
NEW QUESTION 66
A 58-year-old man recently diagnosed with chronic stable angina has discontinued metoprolol due to erectile dysfunction. Medical history also includes hypertension and type 2 diabetes mellitus. The patient's current medications include aspirin, lisinopril, metformin, and sublingual nitroglycerin as needed. BP is 128/76 mm Hg, and HR 88 bpm.
Which of the following is the most appropriate choice to manage the patient's stable angina symptoms?
- A. Atenolol
- B. Diltiazem CD
- C. Vardenafil
- D. Amlodipine
Answer: B
NEW QUESTION 67
A 74-year-old man has been diagnosed with acute bacterial prostatitis. He has no known drug allergies. Which of the following is the optimal therapy duration with levofloxacin 500 mg daily?
- A. 3-5 days
- B. 6-8 Weeks
- C. 7-10 days
- D. 2-4 Weeks
Answer: D
NEW QUESTION 68
A patient presents with palpitations and shortness of breath. A 12-lead ECG reveals a regular narrow QRS complex supraventricular tachycardia. What is the recommended first-line therapy?
- A. Amiodarone
- B. Verapamil
- C. Adenosine
- D. Lidocaine
Answer: C
NEW QUESTION 69
A 38-year-old man with stage II testicular cancer has received a 5-day course of Cisplatin and etoposide, followed by daily Filgrastim. On day 14, he reports duki aching bone pain. Which of the following is the most likely cause of this complaint?
- A. Etoposide
- B. Disease progression
- C. Cisplatin
- D. Filgrastim
Answer: D
NEW QUESTION 70
Administration of a marketed drug to a patient for an off-label indication without approval from a local IRB is permissible in which of the following situations?
- A. The patient's physician considers that the risk/benefit ratio favors the use of the drug.
- B. The patient's physician has filed a Notice of Claimed Investigational Exemption for a New Drug with the FDA.
- C. The drug is administered under a protocol sponsored by an NIH grant.
- D. The drug is administered on the request of the patient or the patient's representative.
Answer: A
NEW QUESTION 71
A physician suspects that a patient's symptoms are related to abrupt discontinuation of a certain drug and asks the pharmacotherapy specialist about common reactions in this type of situation.
A literature search produces one case report of a discontinuation syndrome involving the drug.
What is the most appropriate action to take with regard to the current suspected adverse event?
- A. Report the event to the FDA MedWatch program.
- B. Complete a manufacturer's adverse event report.
- C. Write and submit a case report detailing the event.
- D. Report the event to the P & T Committee.
Answer: C
NEW QUESTION 72
Which of the following is a risk factor for the development of multidrug resistance in pathogens that cause nosocomial pneumonia?
- A. Current hospitalization for the past 3 days
- B. Hemodialysis initiated 2 days ago
- C. Antimicrobial therapy implemented 6 months ago
- D. Home infusion therapy that includes antibiotics
Answer: B
NEW QUESTION 73
A MEDLINE search fails to retrieve a clinical trial known by the searcher to have been published in a recently established open-access medical journal. This failure has most likely occurred because of which of the following?
- A. The time that the journal has been available does not meet criteria for indexing.
- B. MEDLINE does not index open-access journals.
- C. The searcher limited the search to "humans" and "English language."
- D. MEDLINE selectively indexes articles of the highest scientific merit.
Answer: A
NEW QUESTION 74
Which statement regarding vaccine administration in infants and children is correct?
- A. There is no limit to the number of vaccines an individual may receive at one visit.
- B. The appropriate administration site is the deltoid.
- C. Live Vaccines should be administered at least 2 Weeks before killed Vaccines in infants less than 6 months old.
- D. The vaccines may be combined in the same syringe.
Answer: B
NEW QUESTION 75
A 60-year-old man who is HIV-positive describes symptoms of erectile dysfunction and requests therapy. Current medications include tenofovir 300 mg orally daily, emtricitabine 200 mg orally daily, atazanavir 300 mg orally daily, and ritonavir 100 mg orally daily. In addition to counseling on preventing HIV transmission, which recommendation is appropriate?
- A. Start sildenafil 25 mg/dose (maximum 25 mg in 48 hours) and decrease atazanavir to
150 mg orally daily. - B. Start sildenafil 25 mg/dose (maximum 25 mg in 48 hours).
- C. Start sildenafil 50 mg/dose (maximum 200 mg in 48 hours) and decrease atazanavir to
150 mg orally daily. - D. Start sildenafil 50 mg/dose (maximum 200 mg in 48 hours).
Answer: B
NEW QUESTION 76
A 50-year-old woman experienced acute renal failure after receiving contrast dye for an imaging study. Her estimated creatinine clearance is now 20 mL/min. Her medications include:
* Piperacillin/tazobactam 4.5g intravenously every 8 hours
* Azithromycin 500 mg intravenously daily
* Famotidine 40 mg orally twice daily
* Enoxaparin 40 mg subcutaneously daily
* Metoprolol succinate 100 mg orally daily
Which drugs require dose reduction due to acute renal failure?
- A. Piperacillin/tazobactam, famotidine, and metoprolol succinate
- B. Piperacillin/tazobactam, azithromycin, and enoxaparin
- C. All of her current medications
- D. Piperacillin/tazobactam, famotidine, and enoxaparin
Answer: D
NEW QUESTION 77
According to the Centers for Disease Control and Prevention recommendations, administration of which vaccines must be separated by at least 4 weeks if the vaccines are not administered simultaneously?
- A. Measles, mumps, and rubella (MMR), and Haemophilus influenzae type b (Hib)
- B. Tetanus/diphtheria (Td) and intranasal influenza
- C. Tetanus/diphtheria (Td) and hepatitis A
- D. Measles, mumps, and rubella (MMR), and varicella
Answer: A
NEW QUESTION 78
An article in a clinical pharmacology journal describes a double-blind controlled trial comparing the efficacy of sumatriptan to a placebo injection for intractable migraine which used a 5 point Likert scale to evaluate headaches 2 hours after treatment. Which of the following is the most appropriate statistical test for analyzing the data?
- A. Student's t test
- B. Mann-Whitney U test
- C. Fisher's exact test
- D. Chi-square test
Answer: B
NEW QUESTION 79
A patient with recently diagnosed Iymphoma is receiving doxorubicin, bleomycin, vinblastine, and dacarbazine. Aggressive intravenous hydration is required to decrease the complications associated with which of the following?
- A. Tumor lysis syndrome
- B. Doxorubicin cardiomyopathy
- C. Dacarbazine nephrotoxicity
- D. Bleomycin pulmonary toxicity
Answer: A
NEW QUESTION 80
In designing a clinical trial, the method utilized to deal with inherent differences between groups is to:
- A. Assign patients to groups randomly.
- B. Use a control or comparison group.
- C. Use blinding techniques.
- D. Evaluate the results using statistical methods.
Answer: C
NEW QUESTION 81
Investigators studying the relative nephrotoxicity of two aminoglycosides selected their sample size to detect a reduction in toxicity of 10%. Which of the following is the power of this study if the probability of falsely rejecting the null hypothesis is 0.05 and the probability of falsely accepting the null hypothesis is 0.20?
- A. 0.80
- B. 0.05
- C. 0.95
- D. 0.10
Answer: A
NEW QUESTION 82
A 65-year-old man with heart failure is currently receiving digoxin, lisinopril, furosemide, and carvedilol. He is in normal sinus rhythm and is hemodynamically stable. His left ventricular ejection fraction is 30%. Which of the following statements best describes the role of digoxin therapy in this patient?
- A. It can be safely discontinued.
- B. It can be synergistic with carvedilol.
- C. It can improve mortality.
- D. It can decrease the risk of hospitalization.
Answer: D
NEW QUESTION 83
A patient with hepatic encephalopathy is being treated with lactulose 15 mL four times daily.
Over the next 72 hours, the patient becomes less agitated but remains disoriented. Which of the following should be the next step?
- A. Measure stool pH to ensure that it is greater than 7.
- B. Begin branched-chain amino-acid supplementation.
- C. Determine the frequency of bowel movements.
- D. Add neomycin 1 g four times daily.
Answer: D
NEW QUESTION 84
A patient with a COPD exacerbation is treated with prednisone 40 mg daily for one week with improvement. To discontinue the prednisone, the most appropriate procedure would be which of the following?
- A. Reducing the daily prednisone dose by 50% every other day until it is down to 10 mg daily, then reducing it by 25% every other day until the patient is off the drug.
- B. Reducing the daily prednisone dose by 50% every day until the patient is off the drug.
- C. Reducing the daily prednisone dose by 25% every day until the patient is off the drug.
- D. Stopping prednisone administration without dose tapering.
Answer: D
NEW QUESTION 85
A 65-year-old woman on chronic hemodialysis presents with difficulty breathing and inability to sleep. The patient has had shortness of breath, diaphoresis, and nausea, but has not vomited.
She denies having abdominal pain, diarrhea, or chest pain. She has tachycardia and tachypnea, and exhibits peaked T waves with occasional PVCs on the ECG. Serum chemistry values are:
* Sodium: 137 mEq/L
* BUN: 125 mg/dL
* Potassium: 7.2 mEq/L
* Creatinine: 12.8 mg/dL
* Chloride: 97 mEq/L
* Glucose: 95 mg/dL
* HCO3- : 11 mEq/L
* Calcium: 8.5 mg/dL
* Albumin: 3.1 g/dL
* Phosphorus: 1.7 mg/dL
Which of the following should the pharmacotherapy specialist recommend for immediate therapy?
- A. Sodium polystyrene sulfonate with sorbitol orally
- B. Sodium bicarbonate intravenously
- C. Hemodialysis
- D. Calcium gluconate intravenously
Answer: D
NEW QUESTION 86
Which of the following is an advantage of a crossover-design clinical trial?
- A. Smaller sample size needed
- B. No randomization needed
- C. No carryover effect
- D. No period effect
Answer: B
NEW QUESTION 87
From ethical and scientific validity standpoints, in addition to double blinding, which of the following research designs is best for determining a new medication's relative efficacy in treating acute stroke?
- A. Crossover design comparing the new therapy with the best standard therapy
- B. Placebo-controlled, crossover design
- C. Parallel design comparing the new therapy with the best standard therapy
- D. Placebo-controlled, randomized, parallel design
Answer: A
NEW QUESTION 88
A 72-year-old woman with a long history of schizophrenia has been admitted to the state hospital because of a recent relapse while on risperidone 5 mg daily. It is decided to use an equivalent dose of ziprasidone. Which reference would most likely provide this information?
- A. Martindale: The Complete Drug Reference
- B. Drug Facts & Comparisons
- C. Diagnostic and Statistical Manual of Mental Disorders - V
- D. The Sanford Guide
Answer: A
NEW QUESTION 89
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